The buildings in which Legon Presec was originally started in 1938 which is located in Odumase – Krobo the Municipal capital of Lower Manya Krobo Municipality in the Eastern Region of Ghana before moving to its current location in Legon, Accra in 1968.
Presbyterian Boys’ Secondary School (PRESEC) is a secondary boarding school for boys, in Legon, Accra, Ghana. It was founded in 1938, under the auspices of the Presbyterian Church of the Gold Coast. The progenitor of the original idea for the school was the Basel missionary, Nicholas Timothy Clerk (1862–1961), who served as the first Synod Clerk of the Presbyterian Church of the Gold Coast from 1918 to 1932.
The school has ties with its sister schools, Aburi Girls’ Senior High School and Krobo Girls Senior High School.